Org 2766

ACTH 4-9 (H-Met(O)-Glu-His-Phe-D-Lys-Phe-OH) analog in which 4-Met position of fragment substituted by 4-Met sulfoxide, 8-Arg replaced by 8-D-Lys & 9-Trp replaced by 9-Phe; RN given refers to (D-Lys)-isomer

Also Known As:

ACTH (4-9), methylsulfonylaminobutyryl- Lys(8)- Phe(9)- ; ACTH(4-9), methylsulfonylaminobutyryl- Lysyl(8)- Phenylalanine(9)- ; MSH-ACTH (4-9) analog; Org 2766, (D-Phe)-isomer; Org 2766, (D-alpha-Glu)-isomer; Org 2766, (all-L)-isomer; methylsulfonylaminobutyryl- 8- Lys- 9- Phe- ACTH (4-9); L-phenylalanine, gamma- (methylsulfonyl)- L- alpha- aminobutyryl- L- alpha- glutamyl- L- histidyl- L- phenylalanyl- D- lysyl-

Pharmalogical Action Categories:

D000927 - Anticonvulsants

Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 82104
  - Peptide Hormones: 1361
    - Pituitary Hormones: 610
      - Anterior Pituitary Hormones: 189
        Pro-Opiomelanocortin: 1972
        Melanocortins: 967
        Adrenocorticotropic Hormone: 16722
        Org 2766: 47
    - Hypothalamic Hormones: 69
      - Pro-Opiomelanocortin: 1972
        Melanocortins: 967
        Adrenocorticotropic Hormone: 16722
        Org 2766: 47
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Nerve Tissue Proteins: 3
    - Neuropeptides: 6903
      - Hypothalamic Hormones: 69
        Pro-Opiomelanocortin: 1972
        Melanocortins: 967
        Adrenocorticotropic Hormone: 16722
        Org 2766: 47
- Peptides: 84029
  - Neuropeptides: 6903
    - Hypothalamic Hormones: 69
      - Pro-Opiomelanocortin: 1972
        Melanocortins: 967
        Adrenocorticotropic Hormone: 16722
        Org 2766: 47
  - Peptide Hormones: 1361
    - Pituitary Hormones: 610
      - Anterior Pituitary Hormones: 189
        Pro-Opiomelanocortin: 1972
        Melanocortins: 967
        Adrenocorticotropic Hormone: 16722
        Org 2766: 47
    - Hypothalamic Hormones: 69
      - Pro-Opiomelanocortin: 1972
        Melanocortins: 967
        Adrenocorticotropic Hormone: 16722
        Org 2766: 47
  - Peptide Fragments: 379
    - Org 2766: 47

J E Veldman Selected Research

J E Veldman Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure